Science, explained as simply as possible ... but not simpler
Discovery of an atmosphere on a trans-Neptunian object
Astronomers in Japan have reported in Nature that a trans-Neptunian object (TNO) orbiting the Sun beyond Pluto may have an atmosphere. This is the first evidence of volatile gas on a small body such as a TNO in the outer solar system.
Statin skeptics are losing the argument
My Op-Ed, published at kevinmd.com, on two meta-analyses showing the safety and efficacy of lipid lowering therapy. Are you concerned about statins? In the past two weeks, cold hard statistics have cut through the fog of misinformation surrounding these best-selling drugs, focusing instead on the safety and efficacy of lowering your blood cholesterol level. No emotions or bias, just numbers. Welcome information for anyone who has enjoyed numerous trips around the sun and is looking forward to many more.
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Inflammation & cardiovascular disease: the 2025 ACC Scientific Statement.
The American College of Cardiology has released a scientific statement identifying inflammation as a necessary factor in the development of cardiovascular disease (CVD). It joins the prime suspect, the apoB-containing lipid particles, as an actionable drug target in both primary and secondary populations. The college has called for the widespread adoption of high-sensitivity CRP screening to identify individuals with chronic inflammation, but normal cholesterol, who remain vulnerable to the disease. Read more ...
White Paper - MDMA & chronic pain
Chronic pain affects over 1.5 billion people globally, and is a major contributor to disability, and reduced quality of life. Prolonged opioid-based therapies come with an increased risk of addiction. A non-opioid, non-addictive analgesic is needed to circumvent the short-comings of opioid therapy in a multibillion dollar market .
A new triple drug combination therapy can extend the overall survival time for patients with breast tumours resistant to conventional chemotherapy.
A multinational clinical trial has reported that lepodisiran, a new gene silencing drug, can reduce lipoprotein(a) levels by up to 93.9% compared to placebo.